The Rules:
1. Choose five to seven characters.
2. They may be from books, movies, comics, TV shows, games, and real life--but no traditional superheroes.
3. They may be from any place in the universe, any time. They do not have to be from the same time/place as the original League.
4. You must identify the recruiter, the villain, and the leader, and there must be at least one female.
5. Optional, you may identify their main mode of transportation.
My League:
Villain: The Marquis de Sade (the Quills version).
Leader: Professor Minerva McGonagall (Harry Potter).
Recruiter: Q (Star Trek: The Next Generation, at least originally).
Members: Agent Paul Smecker (The Boondock Saints), Captain Jack Sparrow (PotC, or haven't you been paying attention?), Spider Jerusalem (Transmetropolitan), and Aziraphale (Good Omens).
Transportation: Jack's ship, the Black Pearl.
Good thing I don't have to give them a mission. They'd never get it done, because they'd all kill each other as soon as Aziraphale got sick of mediating.
From: (Anonymous)
Hoedogg's League
Villain: BOB (from Twin Peaks, because he could defeat anyone by simply scaring the living shit out of them)
Leader: Clarice Starling (who definitely earned her stripes in Silence of the Lambs)
Recruiter: The Cowboy (from Mulholland Drive, due to his persuasive skills: "Let's just say I'm driving this buggy, and if you fix your attitude, you can ride with me.")
Members: Pee Wee Herman (Pee Wee's Big Adventure), Furio Giunta (from pre-S4 The Sopranos, before he wussed out), Claire Fisher (Six Feet Under), and Smokey (Friday)
Transportation: The Mystery Machine (Scooby Doo)
I have no idea how these people could possibly function as a team, but it would be simultaneously funny and scary as hell.